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Nematodes - trichostrongyliasis

Introduction, etiology

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Trichostrongyliasis, which results from infection by Trichostrongylus orientalis or other closely related species of nematode worms, affects several million people living mainly in rural communities in Asia.

Dormant eggs can survive for long periods in soil. Once ingested, they release larvae which mature into adult worms within 25-30 days. Most cases are asymptomatic, but heavy infections can cause mild anaemia and enteritis.

Recommended treatments

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albendazole
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chewable tablet, 400 mg

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Adults and children over 2 years:
A single dose of 400 mg
or
pyrantel
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chewable tablet 250 mg (as embonate)
oral suspension, 50 mg (as embonate)/ml

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Adults and children:
A single dose of 10 mg/kg
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Note: levamisole may also be used as treatment

References
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WHO Model Prescribing Information. Drugs used in parasitic diseases second edition, 1995. 146 pages [E, F, S] ISBN 92 4 140104 4 Sw.fr. 35.-/US $31.50. In developing countries Sw.fr.24.50.
  Sales Information: http://www.who.int/bookorders/index.htm
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Intestinal nematodes; WHO link page
   http://www.who.int/health-topics/intestinal.htm
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Report of the WHO Informal Consultation on the use of praziquantel during pregnancy/lactation and albendazole/mebendazole in children under 24 months, Geneva, 8-9 April, 2002, WHO/CDS/CPE/PVC/2002.4
   http://www.who.int/wormcontrol/documents/en/pvc_20024full.pdf
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Benzimidazoles: use in children, Essential Medicines, WHO Drug Information, Vol 17, No. 1, 2003
   http://www.who.int/druginformation/vol17num1_2003/vol17-1.pdf

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